Article
Increased ethanol self-administration in delta-opioid receptor knockout mice.
Alcoholism, clinical and experimental research - 1 Sept 2001
Roberts A J, Gold L H, Polis I, McDonald J S, Filliol D, Kieffer B L, Koob G F
Abstract excerpt
BACKGROUND: The role of the delta-opioid receptor in ethanol drinking has remained unclear despite the use of traditional pharmacological and correlational approaches. The results of several studies suggest that pharmacological blockade of these receptors results in decreases in ethanol drinking behavior, but an approximately equal number of reports have failed to observe an effect of delta-receptor antagonism on...
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