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Article

Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation.

Oncogene - 27 Sept 2001

Xie S, Wang Y, Liu J, Sun T, Wilson M B, Smithgall T E, Arlinghaus R B

Abstract excerpt

We have previously reported that the Jak2 tyrosine kinase but not Jak1 is tyrosine phosphorylated in the absence of IL-3 in Bcr-Abl positive M3.16 cells, which are rendered IL-3 independent by BCR-ABL gene expression. We have explored the involvement of Jak2 tyrosine phosphorylation in Bcr-Abl oncogenic effects. Our results indicate that Jak2 became tyrosine-phosphorylated in a number of cell lines expressing...

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Source

Identifiers

PMID: 11593427
DOI: 10.1038/sj.onc.1204834

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation.PMID 11593427Read ↗

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