Article
Protein phosphatase 2A interacts with the Src kinase substrate p130(CAS).
Oncogene - 20 Sept 2001
Yokoyama N, Miller W T
Abstract excerpt
In this study, we report that the Src substrate Cas (p130 Crk-associated substrate) associates with protein phosphatase 2A (PP2A), a serine/threonine phosphatase. We investigated this interaction in cells expressing a temperature-sensitive mutant form of v-Src. v-Src activation (by shifting cells from the nonpermissive to the permissive temperature) led to an increase in the tyrosine phosphorylation of v-Src and...
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