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Article

Human and Mouse IFN-β Gene Therapy Exhibits Different Anti-tumor Mechanisms in Mouse Models

1 Oct 2001

Abstract excerpt

Previously, we suggested that local human interferon-beta (IFN-beta) gene therapy with replication-defective adenoviral vectors can be an effective cancer treatment. Clinical trials to treat cancers with adenovirus expressing the human IFN-beta gene (IFNB1) has been planned. As a continued effort to explore the mechanisms of action of human IFN-beta gene therapy that can occur in the clinical setting, we tested...

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Identifiers

PMID: 11592839
DOI: 10.1006/mthe.2001.0464

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Source receipt: pubmed, retrieved 7 Sept 2026.

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