Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice.

doi:10.1089/hum.1993.4.6-703

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice.

Human gene therapy - 1 Dec 1993

Haddada H, Ragot T, Cordier L, Duffour M T, Perricaudet M

Abstract excerpt

The murine mastocytoma cell line P815 was used as a model to evaluate the effect on its tumorigenic capacity following interleukin-2 (IL-2) gene transfer into the tumor cells using a replication-defective adenovirus vector. The data show that P815 cells infected in vitro with this recombinant ade...

Topics

Adenoviridae
Animals
Cell Transplantation
Feasibility Studies
Gene Transfer Techniques
Genetic Therapy
Genetic Vectors
Humans
Interleukin-2
Mice
Mice, Inbred DBA
Neoplasms, Experimental
Phenotype
Recombination, Genetic
Spleen
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8186285
DOI: 10.1089/hum.1993.4.6-703

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8186285-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics