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[Characteristics of APC gene mutations in colorectal tumors].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2001

Huang J, Zheng S

Abstract excerpt

OBJECTIVE: To investigate the mutational features of adenomatous polyposis coli (APC) gene and their possible arising mechanism in colorectal tumors. METHODS: PCR-based IVSP assay (in vitro synthesized protein test) and sequence analysis were used to determine somatic mutations of whole APC gene in 115 cases with non familial adenomatous polyposis(non-FAP) colorectal tumors. RESULTS: Seventy-six mutated cases...

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PMID: 11592041

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APC
FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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