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Article

Novel strategies for comprehensive mutation screening of the APC gene.

Neoplasma - 1 Jan 2000

Wachsmannova L, Mego M, Stevurkova V, Zajac V, Ciernikova S

Abstract excerpt

Colorectal cancer is the 4th most common cause of cancer related deaths worldwide and new possibilities in accurate diagnosis and targeted treatment are highly required. Mutations in adenomatous polyposis coli (APC) gene play a pivotal role in adenoma-carcinoma pathway of colorectal tumorigenesis. The quarter century from its´ first cloning, APC became one of the most frequently mutated, known driver genes in...

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Source

Identifiers

PMID: 28253712
DOI: 10.4149/neo_2017_303

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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