Article
Lack of an association of a single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene in Czech women with pregnancy-induced hypertension.
Gynecologic and obstetric investigation - 1 Jan 2001
Jurajda M, Kanková K, Muzik J, Unzeitig V, Drábková M, Izakovicová-Hollá L, Vácha J
Abstract excerpt
In preeclampsia the cytotrophoblast invasion of the decidual vessels is reduced. The endothelia in the decidual vessels may influence cytotrophoblast invasion and remodeling of decidual spiral arteries. The decidual endothelial cells from preeclamptic placentas produce less matrix metalloproteinase-1 (MMP1) than those from normal placentas. MMPs form a group of enzymes that are capable of degrading components of...
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