A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene.

doi:10.1006/mcpr.2001.0398

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Article

A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene.

Molecular and cellular probes - 1 Feb 2002

Jurajda M, Muzík J, Izakovicová Hollá L, Vácha J

Abstract excerpt

Matrix metalloproteinase-1 (MMP-1) is a member of the matrix metalloproteinase enzyme family that degrades components of the extracellular matrix. Recent studies have demonstrated several polymorphic sites in the promoter of the MMP-1 gene. A newly identified single nucleotide polymorphism (SNP) at position -519 in the promoter region of the MMP-1 gene is reported. This polymorphism consists in a guanine to...

Topics

Adult
Aged
Binding Sites
Colorectal Neoplasms
Czech Republic
Female
Gene Frequency
Humans
Male
Matrix Metalloproteinase 1
Middle Aged
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
White People

Source

Open in PubMed

Identifiers

PMID: 12005449
DOI: 10.1006/mcpr.2001.0398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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