Article
Disturbance of normal cell cycle progression enhances the establishment of transcriptional silencing in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jul 1995
Laman H, Balderes D, Shore D
Abstract excerpt
Previous studies have indicated that mutation of RAP1 (rap1s) or of the HMR-E silencer ARS consensus element leads to metastable repression of HMR. A number of extragenic suppressor mutations (sds, suppressors of defective silencing) that increase the fraction of repressed cells in rap1s hmr delt...
Topics
- Cell Cycle
- Cloning, Molecular
- Cyclins
- DNA-Binding Proteins
- Fungal Proteins
- Gene Dosage
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Regulator
- Hydroxyurea
- Kinesins
- Mating Factor
- Microtubule-Associated Proteins
- Mutagenesis
- Mutation
- Peptide Biosynthesis
- Peptides
- Regulatory Sequences, Nucleic Acid