Article
The KEX2 gene of Candida glabrata is required for cell surface integrity.
Molecular microbiology - 1 Sept 2001
Bader O, Schaller M, Klein S, Kukula J, Haack K, Mühlschlegel F, Korting H C, Schäfer W, Hube B
Abstract excerpt
Candida glabrata has emerged as one of the most common causes of candidosis. In order to identify factors that are necessary for viability and pathogenicity of this fungal pathogen, we analysed the role of the KEX2 gene, which codes for a regulatory endoproteinase that is known to process certain virulence factors in Candida albicans. The KEX2 gene from C. glabrata was cloned and found to have 51% and 62%...
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