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Article

A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata.

Proceedings of the National Academy of Sciences of the United States of America - 1 May 2007

Kaur Rupinder, Ma Biao, Cormack Brendan P

Abstract excerpt

Candida glabrata is a yeast pathogen of humans. We have established a tissue culture model to analyze the interaction of C. glabrata with macrophages. Transcript profiling of yeast ingested by macrophages reveals global changes in metabolism as well as increased expression of a gene family (YPS genes) encoding extracellular glycosylphosphatidylinositol-linked aspartyl proteases. Eight of these YPS genes are found...

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Identifiers

PMID: 17456602
DOI: 10.1073/pnas.0611195104
PMCID: PMC1863504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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