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Article

KEX2 influences Candida albicans proteinase secretion and hyphal formation.

The Journal of biological chemistry - 14 Nov 1997

Newport G, Agabian N

Abstract excerpt

Candida albicans possesses at least seven differentially expressed genes that encode virulence-related secretory aspartyl proteinases (Saps). Sap DNA sequences predict post-translational processing at lysine-arginine residues in the preproteins, reminiscent of the maturation of Saccharomyces cerevisiae alpha-factor, where a prepropolypeptide is converted into a biologically active pheromone by Kex2, a...

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PMID: 9360967
DOI: 10.1074/jbc.272.46.28954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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