Silencing of Kex2 significantly diminishes the virulence of Cryphonectria parasitica.

doi:10.1094/MPMI-22-2-0211

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Article

Silencing of Kex2 significantly diminishes the virulence of Cryphonectria parasitica.

Molecular plant-microbe interactions : MPMI - 1 Feb 2009

Jacob-Wilk Debora, Turina Massimo, Kazmierczak Pam, Van Alfen Neal K

Abstract excerpt

Cryphonectria parasitica is the causal agent of chestnut blight. Infection of this ascomycete with Cryphonectria hypovirus 1 (CHV1) results in reduction of virulence and sporulation of the fungus. The virus affects fungal gene expression and several of the CHV1 downregulated genes encode secreted proteins that contain consensus Kex2 processing signals. Additionally, CHV1 has been shown to colocalize in infected...

Topics

Amino Acid Motifs
Amino Acid Sequence
Ascomycota
Blotting, Northern
Blotting, Western
Cyperaceae
Fungal Proteins
Gene Expression Regulation, Fungal
Gene Silencing
Malus
Molecular Sequence Data
Mutation
Plant Stems
Protein Structure, Tertiary
RNA, Small Interfering
Sequence Analysis, DNA
Virulence

Source

Open in PubMed

Identifiers

PMID: 19132873
DOI: 10.1094/MPMI-22-2-0211

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