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Article

A disulfide bond is required for functional assembly of NCX1 from complementary fragments.

Biochemical and biophysical research communications - 5 Oct 2001

Qiu Z, Chen J, Nicoll D A, Philipson K D

Abstract excerpt

The cardiac Na(+)-Ca(2+) exchanger consists of a single polypeptide with two transmembrane segment (TMS) clusters separated by a large intracellular loop between TMS5 and TMS6 (Nicoll et al. (1999) J. Biol. Chem. 274, 910-917; Iwamoto et al. (1999) FEBS Lett. 446, 264-268). A "split" exchanger can be expressed by dividing the exchanger cDNA into two fragments so that the NH(2)- and CO(2)H-terminal portions of the...

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Identifiers

PMID: 11573936
DOI: 10.1006/bbrc.2001.5656

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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