Article
An E3-like factor that promotes SUMO conjugation to the yeast septins.
Cell - 21 Sept 2001
Johnson E S, Gupta A A
Abstract excerpt
Covalent attachment of the ubiquitin-related protein SUMO to other proteins participates in many processes including signal transduction, transcriptional regulation, and growth control. We report the characterization of Siz1 as an E3-like factor in the SUMO pathway. Siz1 is required for SUMO attachment to the S. cerevisiae septins in vivo and strongly stimulates septin sumoylation in vitro. Siz1 and the related...
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