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Article

Bacterial senescence: protein oxidation in non-proliferating cells is dictated by the accuracy of the ribosomes.

The EMBO journal - 17 Sept 2001

Ballesteros M, Fredriksson A, Henriksson J, Nyström T

Abstract excerpt

We have investigated the causal factors behind the age-related oxidation of proteins during arrest of cell proliferation. A proteomic approach demonstrated that protein oxidation in non-proliferating cells is observed primarily for proteins being produced in a number of aberrant isoforms. Also, these cells exhibited a reduced translational fidelity as demonstrated by both proteomic analysis and genetic...

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Identifiers

PMID: 11566891
DOI: 10.1093/emboj/20.18.5280
PMCID: PMC125621

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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