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Article

A chemical approach to mapping nucleosomes at base pair resolution in yeast.

Methods in enzymology - 1 Jan 2012

Brogaard Kristin R, Xi Liqun, Wang Ji-Ping, Widom Jonathan

Abstract excerpt

Most eukaryotic DNA exists in DNA-protein complexes known as nucleosomes. The exact locations of nucleosomes along the genome play a critical role in chromosome functions and gene regulation. However, the current methods for nucleosome mapping do not provide the necessary accuracy to identify the precise nucleosome locations. Here we describe a new experimental approach that directly maps nucleosome center...

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Identifiers

PMID: 22929776
DOI: 10.1016/B978-0-12-391938-0.00014-8
PMCID: PMC5101424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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