Article
cAMP receptor affinity controls wave dynamics, geometry and morphogenesis in Dictyostelium.
Journal of cell science - 1 Jul 2001
Dormann D, Kim J Y, Devreotes P N, Weijer C J
Abstract excerpt
Serpentine G-protein-coupled cAMP receptors are key components in the detection and relay of the extracellular cAMP waves that control chemotactic cell movement during Dictyostelium development. During development the cells sequentially express four closely related cAMP receptors of decreasing affinity. In this study, we investigated the effect of cAMP receptor type and affinity on the dynamics of cell-cell...
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