Article
Psoriasis is associated with a SNP haplotype of the corneodesmosin gene (CDSN).
Tissue antigens - 1 Oct 2002
Orrù S, Giuressi E, Casula M, Loizedda A, Murru R, Mulargia M, Masala M V, Cerimele D, Zucca M, Aste N, Biggio P, Carcassi C, Contu L
Abstract excerpt
A psoriasis susceptibility locus has been mapped to the HLA region in the proximity of the HLA-C locus. This critical region also contains the CDSN gene coding for the corneodesmosin protein. In a case-control association study of psoriasis in the Sardinian population, we analyzed the allele distribution of eight intragenic SNPs (positions 619, 767, 1215, 1118, 1236, 1243, 1331, 1593) of the CDSN gene and the six...
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