Article
Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not in Japanese populations.
Clinical and experimental dermatology - 1 Jul 2005
Ameen M, Allen M H, Fisher S A, Lewis C M, Cuthbert A, Kondeatis E, Vaughan R W, Murakami H, Nakagawa H, Barker J N W N
Abstract excerpt
PSORS1 on chromosome 6p21.3, which contains the MHC, is a major susceptibility locus for psoriasis vulgaris. This region is characterized by strong linkage disequilibrium and contains the corneodesmosin (CSDN) gene, an attractive candidate for psoriasis susceptibility based on its putative biological function in keratinocyte adhesion, and HLA-Cw6, an established marker for psoriasis susceptibility. We compared...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.