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Article

Identification of six novel polymorphisms in the human corneodesmosin gene.

Tissue antigens - 1 Jan 2001

Guerrin M, Vincent C, Simon M, Tazi Ahnini R, Fort M, Serre G

Abstract excerpt

Psoriatic epidermis is characterised by a defective differentiation program leading to an abnormal permeability barrier and impaired desquamation. The corneodesmosin gene (CDSN) or "S" gene is a strong candidate in psoriasis susceptibility, due first to its genomic position ("S" gene, 160 kb telomeric to HLA-C) and second to its expression and function in the epidermis. Moreover, an association between CDSN and...

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Source

Identifiers

PMID: 11169256
DOI: 10.1034/j.1399-0039.2001.057001032.x

Genes

CDSN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Identification of six novel polymorphisms in the human corneodesmosin gene.PMID 11169256Read ↗

Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with psoriasis vulgaris.Semantic proximity Read ↗

Psoriasis is associated with a SNP haplotype of the corneodesmosin gene (CDSN).Semantic proximity Read ↗

S gene (Corneodesmosin) diversity and its relationship to psoriasis; high content of cSNP in the HLA-linked S gene.Semantic proximity Read ↗

Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis.Semantic proximity Read ↗

Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-Kb interval around the corneodesmosin gene (CDSN).Semantic proximity Read ↗

Corneodesmosin gene: no evidence for PSORS 1 gene in North-eastern Thai psoriasis patients.Semantic proximity Read ↗

Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR.Semantic proximity Read ↗

Corneodesmosin DNA polymorphisms in MHC haplotypes and Japanese patients with psoriasis.Semantic proximity Read ↗

Comparative association analysis reveals that corneodesmosin is more closely associated with psoriasis than HLA-Cw*0602-B*5701 in German families.Semantic proximity Read ↗

Inflammatory peeling skin syndrome caused a novel mutation in CDSN.Semantic proximity Read ↗

Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not in Japanese populations.Semantic proximity Read ↗

Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses.Semantic proximity Read ↗

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