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Article

Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells.

The Journal of biological chemistry - 16 Nov 2001

Castro D S, Hermanson E, Joseph B, Wallén A, Aarnisalo P, Heller A, Perlmann T

Abstract excerpt

Dopamine cells are generated in the ventral midbrain during embryonic development. The progressive degeneration of these cells in patients with Parkinson's disease, and the potential therapeutic benefit by transplantation of in vitro generated dopamine cells, has triggered intense interest in understanding the process whereby these cells develop. Nurr1 is an orphan nuclear receptor essential for the development...

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Identifiers

PMID: 11553630
DOI: 10.1074/jbc.M107013200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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