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Article

Proliferative and protective effects of SurR9-C84A on differentiated neural cells.

Journal of neuroimmunology - 8 Oct 2010

Baratchi Sara, Kanwar Rupinder K, Cheung Chun Hei Antonio, Kanwar Jagat R

Abstract excerpt

Targeting survivin has the ability to inhibit apoptosis and regulate mitosis for the protection of neuronal cells, and it offers several advantages for neuronal repair and protection. We found that the BIR motif mutant of survivin (SurR9-C84A) can bind to microtubules and regulate their stability, induce cell division, increase proliferation and activate the expression of cell cycle and neuronal markers in...

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Identifiers

PMID: 20709413
DOI: 10.1016/j.jneuroim.2010.06.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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