Article
Additional candidates to conventional genes susceptible for lung cancer and changing trend in Japan.
Oncology reports - 1 Jun 2010
Okazaki Isao, Sugita Minoru, Matsuki Hideaki, Billah Syed Muhammad Baqui, Watanabe Tetsu
Abstract excerpt
The polymorphism of CYP1A1*2A or CYP1A1*2B, and the linkage of CYP1A1*2A, CYP1A1*2B, GSTM1 and GSTT1 polymorphisms have been established as susceptible genes or gene-gene interactions of tobacco-related lung cancer. New candidate genes susceptible for lung cancer such as NQO1 (NAD(P)H:quinine oxidoreductase), NAT2 (N-acetyltransferase 2), and several others have been reported. In the present review we focus on...
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