Article
Genetic polymorphism of xenobiotic metabolizing enzymes among Chinese lung cancer patients.
International journal of cancer - 5 May 1999
Persson I, Johansson I, Lou Y C, Yue Q Y, Duan L S, Bertilsson L, Ingelman-Sundberg M
Abstract excerpt
Polymorphisms in xenobiotic metabolizing enzymes have been implicated in inter-individual and inter-ethnic differences in cancer susceptibilty. Several studies have indicated an association between variant alleles of the human CYP1A1, CYP2E1 and GSTM1 genes and lung cancer. Activity of microsomal epoxide hydrolase (HYL1) has also been associated with lung cancer, and 2 variant alleles causing amino acid...
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