Article
Cytochrome P4501A2 (CYP1A2) activity and lung cancer risk: a preliminary study among Chinese women in Singapore.
Carcinogenesis - 1 Apr 2001
Seow A, Zhao B, Lee E J, Poh W T, Teh M, Eng P, Wang Y T, Tan W C, Lee H P
Abstract excerpt
There is increasing evidence for the role of heterocyclic and other arylamines in carcinogenesis, including lung carcinogenesis. Chinese women have a high rate of lung cancer despite a low smoking prevalence, and studies in this population may provide useful information on risk factors other than smoking. Hepatic CYP1A2 and NAT2 are involved in the metabolism of carcinogenic arylamines, and NAT2 also catalyzes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
