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Article

Modulation of pulmonary alveolar type II cell phenotype and communication by extracellular matrix and KGF.

American journal of physiology. Cell physiology - 1 Oct 2001

Isakson B E, Lubman R L, Seedorf G J, Boitano S

Abstract excerpt

The alveolar epithelium consists of two cell types, alveolar type I (AT1) and alveolar type II (AT2) cells. We have recently shown that 7-day-old cultures of AT2 cells grown on a type I collagen/fibronectin matrix develop phenotypic characteristics of AT1 cells, display a distinct connexin profile, and coordinate mechanically induced intercellular Ca(2+) changes via gap junctions (25). In this study, we cultured...

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Identifiers

PMID: 11546667
DOI: 10.1152/ajpcell.2001.281.4.C1291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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