Article
Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin 5.
American journal of respiratory cell and molecular biology - 1 Apr 1998
Borok Z, Lubman R L, Danto S I, Zhang X L, Zabski S M, King L S, Lee D M, Agre P, Crandall E D
Abstract excerpt
We investigated the role of keratinocyte growth factor (KGF) in regulation of alveolar epithelial cell (AEC) phenotype in vitro. Effects of KGF on cell morphology, expression of surfactant apoproteins A, B, and C (SP-A, -B, and -C), and expression of aquaporin 5 (AQP5), a water channel present in situ on the apical surface of alveolar type I (AT1) cells but not expressed in alveolar type II (AT2) cells, were...
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