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Article

Cellular mechanisms for amyloid beta-protein activation of rat cholinergic basal forebrain neurons.

Journal of neurophysiology - 1 Sept 2001

Jhamandas J H, Cho C, Jassar B, Harris K, MacTavish D, Easaw J

Abstract excerpt

The deposition of amyloid beta-protein (Abeta) in the brain and the loss of cholinergic neurons in the basal forebrain are two pathological hallmarks of Alzheimer's disease (AD). Although the mechanism of Abeta neurotoxicity is unknown, these cholinergic neurons display a selective vulnerability...

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Identifiers

PMID: 11535679
DOI: 10.1152/jn.2001.86.3.1312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11535679-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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