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Article

beta -Amyloid peptide-induced apoptosis regulated by a novel protein containing a g protein activation module.

The Journal of biological chemistry - 1 Jun 2001

Kajkowski E M, Lo C F, Ning X, Walker S, Sofia H J, Wang W, Edris W, Chanda P, Wagner E, Vile S, Ryan K, McHendry-Rinde B, Smith S C, Wood A, Rhodes K J, Kennedy J D, Bard J, Jacobsen J S, Ozenberger B A

Abstract excerpt

Degeneration of neurons in Alzheimer's disease is mediated by beta-amyloid peptide by diverse mechanisms, which include a putative apoptotic component stimulated by unidentified signaling events. This report describes a novel beta-amyloid peptide-binding protein (denoted BBP) containing a G protein-coupling module. BBP is one member of a family of three proteins containing this conserved structure. The BBP...

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PMID: 11278849
DOI: 10.1074/jbc.M011161200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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