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Article

Influence of genetic polymorphisms of styrene-metabolizing enzymes on the levels of urinary biomarkers of styrene exposure.

Toxicology letters - 4 Mar 2015

Carbonari Damiano, Mansi Antonella, Proietto Anna Rita, Paci Enrico, Bonanni Rossana Claudia, Gherardi Monica, Gatto Maria Pia, Sisto Renata, Tranfo Giovanna

Abstract excerpt

Styrene exposure is still present in different occupational settings including manufacture of synthetic rubber, resins, polyesters and plastic. The aim of this work was to investigate the effects of polymorphic genes CYP2E1, EPHX1, GSTT1, and GSTM1 on the urinary concentrations of the styrene metabolites mandelic acid (MA), phenylglyoxylic acid (PGA) and on the concentration ratios between (MA+PGA) and urinary...

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Source

Identifiers

PMID: 25562543
DOI: 10.1016/j.toxlet.2015.01.002

Genes

EPHX1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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