Article
The role of various biomarkers in the evaluation of styrene genotoxicity.
Cancer detection and prevention - 1 Jan 2003
Vodicka P, Koskinen M, Stetina R, Soucek P, Vodickova L, Matousu Z, Kuricova M, Hemminki K
Abstract excerpt
We evaluated our data on the occupational exposure to styrene in lamination workers. The battery of parameters included markers of external and internal exposure and biomarkers of biological effects and susceptibility. DNA repair capacities have been determined in both exposed and control groups. Styrene workplace concentration significantly correlated with styrene concentration in blood, exhaled air and urinary...
Topics
- Adult
- Biomarkers
- Cytochrome P-450 CYP2E1
- DNA Adducts
- DNA Damage
- DNA Mutational Analysis
- DNA Repair
- Female
- Genotype
- Glutathione Transferase
- Humans
- Hypoxanthine Phosphoribosyltransferase
- Male
- Middle Aged
- Occupational Exposure
- Oxidative Stress
- Polymorphism, Genetic
- Styrene
