Article
Cytogenetic biomarkers, urinary metabolites and metabolic gene polymorphisms in workers exposed to styrene.
Pharmacogenetics and genomics - 1 Feb 2006
Migliore Lucia, Naccarati Alessio, Coppedè Fabio, Bergamaschi Enrico, De Palma Giuseppe, Voho Anu, Manini Paola, Järventaus Hilkka, Mutti Antonio, Norppa Hannu, Hirvonen Ari
Abstract excerpt
The present study comprised a biomonitoring study in 95 workers occupationally exposed to styrene and 98 unexposed controls, employing an integrated approach involving biomarkers of exposure, effect, and susceptibility. Airborne styrene was evaluated at workplace, and urinary styrene metabolites, mandelic acid (MA), phenylglyoxylic acid (PGA), vinylphenols (VPTs) and phenylhydroxyethylmercapturic acids (PHEMAs),...
Topics
- Chromosome Aberrations
- Cytogenetics
- Female
- Genetic Markers
- Genotype
- Glyoxylates
- Humans
- In Situ Hybridization, Fluorescence
- Male
- Mandelic Acids