Article
Identification of a site on mannan-binding lectin critical for enhancement of phagocytosis.
The Journal of biological chemistry - 16 Nov 2001
Arora M, Munoz E, Tenner A J
Abstract excerpt
Mannan-binding lectin (MBL) constitutes an important part of the human innate immune defense system. It has been shown to mediate the activation of complement upon binding to specific microbial carbohydrate motifs, to directly opsonize organisms, and to enhance the phagocytosis of targets suboptimally opsonized with IgG or complement components C3b or C4b. This enhancement of phagocytic activity induced by MBL...
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