Article
Pro- and anti-inflammatory cytokines gene polymorphisms and Helicobacter pylori infection: interactions influence outcome.
Cytokine - 21 Feb 2005
Zambon Carlo-F, Basso Daniela, Navaglia Filippo, Belluco Claudio, Falda Alessandra, Fogar Paola, Greco Eliana, Gallo Nicoletta, Rugge Massimo, Di Mario Francesco, Plebani Mario
Abstract excerpt
The aim of this study was to evaluate whether there was any correlation between Helicobacter pylori-associated diseases and (1) H. pylori virulence genes or (2) IL-1B, IL-1RN, IFN-G, TNF-A, IL-10 genetic polymorphisms. Patients with non-cardia gastric cancer (NCGC, n=129) or benign gastroduodenal diseases (n=792) were studied. IL-1RN intron 2 VNTR polymorphism (PCR), IL-1B -31 C/T (RFLP), the SNPs of IFN-G (+874...
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