Article
Role of host interleukin 1beta gene (IL-1B) and interleukin 1 receptor antagonist gene (IL-1RN) polymorphisms in clinical outcomes in Helicobacter pylori-positive Turkish patients with dyspepsia.
Journal of gastroenterology - 1 Jan 2008
Erzin Yusuf, Koksal Vedat, Altun Sibel, Dobrucali Ahmet, Aslan Mustafa, Erdamar Sibel, Goksel Süha, Dirican Ahmet, Kocazeybek Bekir
Abstract excerpt
BACKGROUND: Helicobacter pylori infection leads to different clinical outcomes depending on both host and bacterial factors. In a recent study, we identified H. pylori cagE and babA2 genotypes as independent predictors of duodenal ulcer (DU) and gastric cancer (GC) in dyspepsia patients, but no previous studies have examined the role of host-related genetic factors in Turkey. This time our aim was to evaluate...
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