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Article

SIV infection of macaques as a model for AIDS pathogenesis.

International reviews of immunology - 1 Jan 1992

Johnson P R, Hirsch V M

Abstract excerpt

Simian immunodeficiency virus (SIV) infection of macaques is the best available animal model for studying the pathogenesis of AIDS. Experimental inoculation of macaques with SIV results in a persistent infection that leads to immunodeficiency, opportunistic infections, and death. Most aspects of the illness, including immunologic and virologic parameters, are easily quantified. Furthermore, pathologic processes...

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Identifiers

PMID: 1573320
DOI: 10.3109/08830189209056641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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