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Article

Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver.

Physiological reviews - 1 Jan 2008

Friedman Scott L

Abstract excerpt

The hepatic stellate cell has surprised and engaged physiologists, pathologists, and hepatologists for over 130 years, yet clear evidence of its role in hepatic injury and fibrosis only emerged following the refinement of methods for its isolation and characterization. The paradigm in liver injury of activation of quiescent vitamin A-rich stellate cells into proliferative, contractile, and fibrogenic...

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Identifiers

PMID: 18195085
DOI: 10.1152/physrev.00013.2007
PMCID: PMC2888531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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