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Article

Long-QT syndrome-associated missense mutations in the pore helix of the HERG potassium channel.

Circulation - 28 Aug 2001

Huang F D, Chen J, Lin M, Keating M T, Sanguinetti M C

Abstract excerpt

BACKGROUND: Mutations in the human ether-à-go-go-related gene (HERG) cause chromosome 7-linked long-QT syndrome (LQTS), an inherited disorder of cardiac repolarization that predisposes affected individuals to arrhythmia and sudden death. METHODS AND RESULTS: Here, we characterize the physiologica...

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Source

Identifiers

PMID: 11524404
DOI: 10.1161/hc3501.093815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11524404-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Long-QT syndrome-associated missense mutations in the pore helix of the HERG potassium channel.PMID 11524404Read ↗

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