Article
Male hybrid sterility of mice with the genomic region of the KitW mutation and the KitS allele from Mus spretus.
Biochemical genetics - 1 Apr 2001
el-Shazly S, Seo K W, el-Nahas A, Ables G P, Asano A, Watanabe T
Abstract excerpt
Two congenic strains, C57BL-KitW and C57BL-KitS, were generated. The KitW allele originated from strain WB-KitW and the KitS allele from Mus spretus. The KitW/KitS males showed hybrid sterility with small testes, but the females were fertile. The development of the seminiferous tubules of KitW/KitS males stopped before the spermatocyte stage and they were almost free of sperm. The Kit gene is located at position...
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