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Article

A novel Kit gene mutation in CF1 mice involved in the extracellular domain of the KIT protein.

Experimental animals - 1 Jan 2012

Takabayashi Shuji, Nishikawa Tetsu, Katoh Hideki

Abstract excerpt

We screened for natural mutations in Crl:CF1 closed colony mice using an ordinary backcrossing system. Five of 30 CF1 males carried novel genes that caused white spots on colored coats. Their backcross progenies showed a white spot phenotype. The white spot gene was mapped to approximately 39 cM on chromosome 5, where the Kit gene is known to reside. Allelism testing between this spot gene and the Kit gene was...

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Share to Mice, Congenic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation, Missense

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Share to Proto-Oncogene Proteins c-kit

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Source

Identifiers

PMID: 22850643
DOI: 10.1538/expanim.61.435

Genes

KIT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel Kit gene mutation in CF1 mice involved in the extracellular domain of the KIT protein.PMID 22850643Read ↗

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