Article
Allele 2 of interleukin-1 receptor antagonist gene increases the risk of thyroid peroxidase antibodies in subacute thyroiditis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jun 2001
Luotola K, Mantula P, Salmi J, Haapala A M, Laippala P, Hurme M
Abstract excerpt
Subacute granulomatous thyroiditis (SAT) is a self-limiting systemic inflammatory disorder with possible transient expression of thyroid antibodies. Persistent hypothyroidism is uncommon. The interleukin-1 receptor antagonist IL-1ra is an inhibitor of IL-1 activity and allele 2 of the IL-1ra gene is associated with inflammatory diseases and IL-1ra production. Forty-eight subjects with SAT were investigated....
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