Article
Interleukin-1β and interleukin-1receptor antagonist polymorphisms in Egyptian children with febrile seizures: A case-control study.
Medicine - 1 Mar 2017
Al Morshedy Salah, Elsaadany Hosam F, Ibrahim Hany E, Sherif Ashraf M, Farghaly Mohsen A A, Allah Mayy A N, Abouzeid Heba, Elashkar Shaimaa S A, Hamed Mohammed E, Fathy Manar M, Khalil Atef M, Noah Maha A, Hegab Mohamed S, Ahmed Ahmed R, Hashem Mustafa I A, Emam Ahmed A, Anany Heba G, Ibrahim Boshra R, Gawish Heba H, Nabil Rehab M, Fattah Lobna Abdel, Alsayed Salah F
Abstract excerpt
Febrile seizure is the most common seizure disorder of childhood. Of the pro-inflammatory cytokines, interleukin-1 is defined as the first endogenous pyrogen.We designed this study to investigate single-nucleotide polymorphisms (SNPs) situated at positions -31 (C/T), and -511 (C/T) of interleukin-1beta (IL-1β) gene promoter and interleukin-1receptor antagonist (IL-1RA) gene variable number of tandem repeats in...
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