Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aciclovir selects for ganciclovir-cross-resistance of human cytomegalovirus in vitro that is only in part explained by known mutations in the UL97 protein.

Journal of medical virology - 1 Sept 2001

Michel D, Höhn S, Haller T, Jun D, Mertens T

Abstract excerpt

Phenotypically, ganciclovir-resistant human cytomegalovirus strains could be selected by aciclovir as effectively as by ganciclovir in vitro. Three clinical human cytomegalovirus isolates with different sensitivities against ganciclovir, aciclovir, foscarnet, and cidofovir, but without any mutation in the viral UL97 protein known to confer ganciclovir resistance, were propagated each in duplicate in the presence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyclovir
Share to Cross Reactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytomegalovirus

Share to Cytomegalovirus Infections

Share to Drug Resistance, Microbial

Share to Drug Resistance, Multiple

Share to Ganciclovir

Share to Phosphotransferases (Alcohol Group Acceptor)

Source

Identifiers

PMID: 11505446

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aciclovir selects for ganciclovir-cross-resistance of human cytomegalovirus in vitro that is only in part explained by known mutations in the UL97 protein.PMID 11505446Read ↗

The biology of cytomegalovirus drug resistance.Semantic proximity Read ↗

Genotypic and Phenotypic Study of Antiviral Resistance Mutations in Refractory Cytomegalovirus Infection.Semantic proximity Read ↗

Antiviral Drug Resistance of Human CytomegalovirusSemantic proximity Read ↗

Ganciclovir and maribavir cross-resistance revisited: Relative drug susceptibilities of canonical cytomegalovirus mutants.Semantic proximity Read ↗

Resistance of human cytomegalovirus to antiviral drugs.Semantic proximity Read ↗

Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility.Semantic proximity Read ↗

Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma.Semantic proximity Read ↗

Human cytomegalovirus antiviral drug resistance in hematopoietic stem cell transplantation: current state of the art.Semantic proximity Read ↗

The genetic basis of human cytomegalovirus resistance and current trends in antiviral resistance analysis.Semantic proximity Read ↗

Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs.Semantic proximity Read ↗

Opposite effects of cytomegalovirus UL54 exonuclease domain mutations on acyclovir and cidofovir susceptibility.Semantic proximity Read ↗

Antiviral drug resistance in human cytomegalovirus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.