Article
The genetic basis of human cytomegalovirus resistance and current trends in antiviral resistance analysis.
Infectious disorders drug targets - 1 Oct 2011
James S H, Prichard M N
Abstract excerpt
Infections due to resistant human cytomegalovirus (CMV) are an emerging problem, particularly in immunocompromised hosts. When managing such patients, clinicians should be aware of the possibility of developing CMV antiviral resistance, especially while on prolonged therapy or if severe immunosuppression is present. CMV resistance to current antiviral agents is mediated by alterations in either the UL97 kinase or...
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