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Article

Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1.

Pharmacogenetics - 1 Aug 2001

Fretland A J, Doll M A, Leff M A, Hein D W

Abstract excerpt

N-acetyltransferase 1 (NAT1) catalyses the activation and/or deactivation of aromatic and heterocyclic amine carcinogens. A genetic polymorphism in NAT1 is associated with an increased risk of various cancers and drug toxicities, but epidemiological investigations are severely compromised by a poor understanding of the relationship between NAT1 genotype and phenotype. Human reference NAT1*4 and 12 known human...

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Source

Identifiers

PMID: 11505221
DOI: 10.1097/00008571-200108000-00006

Genes

NAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1.PMID 11505221Read ↗

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