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Article

Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1.

The pharmacogenomics journal - 1 Oct 2008

Zhu Y, Hein D W

Abstract excerpt

Genetic variants of human N-acetyltransferase 1 (NAT1) are associated with cancer and birth defects. N- and O-acetyltransferase catalytic activities, Michaelis-Menten kinetic constants (K(m) and V(max)) and steady-state expression levels of NAT1-specific mRNA and protein were determined for the reference NAT1*4 and variant human NAT1 haplotypes possessing single nucleotide polymorphisms (SNPs) in the open reading...

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Identifiers

PMID: 17909564
DOI: 10.1038/sj.tpj.6500483
PMCID: PMC2575040

Genes

NAT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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