Article
Haemodynamic characterization of young normotensive men carrying the 825T-allele of the G-protein beta3 subunit.
Pharmacogenetics - 1 Aug 2001
Schäfers R F, Nürnberger J, Rütz A, Siffert W, Wenzel R R, Mitchell A, Philipp T, Michel M C
Abstract excerpt
A C825T polymorphism was recently identified in the gene for the G-protein beta3 subunit, the T-allele being associated with hypertension. To better understand the underlying pathophysiological mechanisms, we compared the haemodynamics of young healthy males with and without the T-allele. In three studies, subjects were investigated with regard to cardiac and vascular function at rest and following intravenous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
