Article
Human telomerase RNA-protein interactions.
Nucleic acids research - 15 Aug 2001
Bachand F, Triki I, Autexier C
Abstract excerpt
Telomere length is maintained in most eukaryotic cells by telomerase. The core components of this ribonucleoprotein (RNP) enzyme include a protein catalytic subunit, composed of motifs conserved among reverse transcriptases (RT), and an RNA subunit that contains a short template sequence essential for the synthesis of telomeric repeats. We developed an electrophoretic mobility shift assay using active telomerase...
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